The drugs we have and the drugs we need against major helminth infections.

Parasitic worms (helminths) have accompanied humans for thousands of years and, still today, they are pervasive where poverty persists, including...

Adv Parasitol 07-14-2010

An enzyme-linked immunosorbent assay as screening tool for human intestinal capillariasis.

% of trichuriasis, and 4.2% of opisthorchiasis sera. The ELISA and immunoblot were in agreement in 91.1% of the sera tested...

Southeast Asian J Trop Med Public Health 06-28-2010

Trichuriasis colitis detected by Doppler sonography.

Trichuriasis affects children at an estimated prevalence rate of 17% in the world population. It sometimes affects the colon and causes...

Pediatr Radiol 06-23-2010

[Prevalence of Schistosoma mansoni infection in two municipalities of the State of Alagoas, Brazil]

... other parasitic diseases was significant in relation to trichuriasis...

Rev Soc Bras Med Trop 06-21-2010

Chronic intestinal helminth infections are associated with immune hyporesponsiveness and induction of a regulatory network.

Helminth infections have been associated with protection against allergy and autoimmune diseases. We investigated the effects of chronic infections...

Infect Immun 06-17-2010

Exploitation of the intestinal microflora by the parasitic nematode Trichuris muris.

The inhabitants of the mammalian gut are not always relatively benign commensal bacteria but may also include larger and more parasitic organisms,...

Science 06-11-2010

Foodborne Nematodal Infections in Hospitalized Patients from a Southwestern Romanian County.

... ascariasis, 7 (2.6%) with trichuriasis, and 2 (0.8%) with ascariasis and trichuriasis coinfections. Geohelminthic infections prevailed in...

Foodborne Pathog Dis 05-11-2010

Activating and inhibitory functions for the histone lysine methyltransferase G9a in T helper cell differentiation and function.

Accumulating evidence suggests that the regulation of gene expression by histone lysine methylation is crucial for several biological processes...

J Exp Med 05-11-2010

IL25 elicits a multipotent progenitor cell population that promotes T(H)2 cytokine responses.

CD4(+) T helper 2 (T(H)2) cells secrete interleukin (IL)4, IL5 and IL13, and are required for immunity to gastrointestinal helminth infections...

Nature 04-29-2010

Mucin gene deficiency in mice impairs host resistance to an enteric parasitic infection.

BACKGROUND & AIMS: Hyperplasia of mucin-secreting intestinal goblet cells accompanies a number of enteric infections, including infections by...

Gastroenterology 04-26-2010